Comorbidities according to the claims data in patients with axial spondyloarthritis in different age groups
| Age (years) | ||||||
| 18–29, n=80 | 30–39, n=207 | 40–49, n=361 | 50–59, n=376 | 60–69, n=372 | 70–79, n=340 | |
| Cardiovascular diseases (%) | ||||||
| Hypertensive diseases (I10–I15) | 2.1 | 13.6 | 31.7 | 48.9 | 65.4 | 84.7 |
| Ischaemic heart diseases (I20–I25) | – | – | 1.6 | 6.4 | 16.5 | 33.7 |
| Diseases of arteries (I70–I79) | 1.4 | 1.4 | 3.6 | 4.8 | 15.6 | 19.7 |
| Diseases of veins (I80–I89) | 4.2 | 7.5 | 14.4 | 17.5 | 22.2 | 27.2 |
| Mental disorders (%) | ||||||
| Depressive disorders (F32, F33) | 13.9 | 17.6 | 21.6 | 27.9 | 20.9 | 20.5 |
| Anxiety disorders (F40, F41) | 6.4 | 9.0 | 8.1 | 12.5 | 8.9 | 8.1 |
| Reaction to severe stress and adjustment disorders (F43) | 6.0 | 10.6 | 11.2 | 13.5 | 9.1 | 4.9 |
| Somatoform disorders (F45) | 13.1 | 16.3 | 23.3 | 25.2 | 17.7 | 21.8 |
| Neurological disorders (%) | ||||||
| Nerve, nerve root and plexus disorders (G50–G59) | 3.5 | 5.7 | 9.6 | 14.0 | 13.2 | 13.4 |
| Polyneuropathies (G60–G64) | – | 2.0 | 3.6 | 6.4 | 10.5 | 17.4 |
| Sleep disorders (G47) | – | 4.9 | 6.9 | 9.6 | 11.3 | 15.8 |
| Obstructive sleep apnoea (G47.31) | – | – | 1.4 | 2.4 | 4.6 | 5.0 |
| Musculoskeletal disorders (other than axSpA) (%) | ||||||
| Osteoarthritis (M15–M19) | 3.9 | 11.6 | 19.4 | 34.8 | 47.0 | 57.6 |
| Spondylosis (M47) | 17.7 | 16.4 | 20.4 | 24.4 | 25.8 | 30.4 |
| Other soft tissue disorders, not elsewhere classified (M79) | 20.9 | 29.5 | 27.8 | 28.4 | 25.7 | 22.8 |
| Fibromyalgia (M79.7) | 2.1 | 2.5 | 4.0 | 5.8 | 4.8 | 4.3 |
| Disorders of bone density (M80–M85) | 2.1 | 4.2 | 5.5 | 13.6 | 19.6 | 18.6 |
| Metabolic and endocrine disorders (%) | ||||||
| Disorders of thyroid gland (E00–E07) | 9.2 | 14.9 | 26.4 | 29.6 | 36.4 | 29.5 |
| Diabetes mellitus (E10–E14) | – | 4.8 | 9.0 | 13.1 | 21.3 | 30.6 |
| Type 2 diabetes mellitus (E11) | – | 1.8 | 7.7 | 11.3 | 18.6 | 28.0 |
| Overweight (E65–E68) | 5.7 | 10.8 | 13.0 | 14.6 | 15.6 | 19.2 |
| Respiratory tract diseases (%) | ||||||
| Chronic obstructive pulmonary disease (J44) | – | 1.0 | 5.2 | 7.4 | 13.2 | 14.2 |
| Asthma bronchiale (J45) | 8.1 | 10.7 | 11.7 | 9.8 | 10.7 | 7.7 |
| Gastrointestinal diseases (%) | ||||||
| Diseases of oesophagus, stomach and duodenum (K20–K31) | 19.2 | 13.7 | 19.7 | 25.3 | 25.8 | 32.6 |