Incidence of adverse drug reactions caused by trimethoprim/sulfamethoxazole prophylaxis
| Number of cases* | Incidence rate (95% CI)† | |
| Adverse drug reactions | 34 | 20.6 (14.3 to 28.6) |
| Anaemia | 2 | 1.2 (0.1 to 4.2) |
| Leucopenia | 1 | 0.6 (0.0 to 3.3) |
| Thrombocytopenia | 3 | 1.8 (0.4 to 5.2) |
| GI problems | 2 | 1.2 (0.1 to 4.2) |
| LFT abnormality | 6 | 3.5 (1.3 to 7.7) |
| Skin rash | 6 | 3.5 (1.3 to 7.7) |
| Azotaemia | 5 | 3.0 (1.0 to 7.1) |
| Hyperkalaemia | 3 | 1.8 (0.4 to 5.2) |
| Others‡ | 6 | 3.5 (1.3 to 7.7) |
| Serious adverse drug reactions | 2 | 1.2 (0.1 to 4.2) |
| Pancytopenia | 1 | 0.6 (0.0 to 3.3) |
| Stevens-Johnson syndrome | 1 | 0.6 (0.0 to 3.3) |
*Total observation period was 170.1 person-years for 262 cases.
†Rate per 100 person-years.
‡Including headache (1), anorexia (1), eosinophilia (1), tingling sensation (1) and pruritus (2).
GI, gastrointestinal; LFT, liver function test.