Table 4

IL19 SNPs associated with stroke/MI in rheumatoid arthritis

SNPLocusM/mMAFOR (95% CI)P values
rs17581834IL19C/T0.12/0.052.7 (1.5 to 5.2)1.1×10−3
rs11119598IL19A/G0.11/0.052.5 (1.4 to 4.6)3.1×10−3
rs74148801IL19C/T0.11/0.052.6 (1.4 to 4.8)2.1×10−3
  • Logistic regression analysis between the three IL19 risk variants and stroke/MI in rheumatoid arthritis (genetic data available for 71 RA patients with and 753 without stroke/MI after RA-disease onset).

  • IL, interleukin; MAF, minor allele frequency for cases/controls; M/m, major/minor alleles; MI, myocardial infarction; P, p value unadjusted; SNP, single nucleotide polymorphism.