Receiver operating characteristic analyses results, estimating sensitivity and specificity of perfusion measures in differentiating healthy participants (n=31), systemic lupus erythematosus (SLE) control (n=39), patients with primary neuropsychiatric SLE (NPSLE) (n=37) and secondary NPSLE (n=16)
| AUC (P) | Sensitivity for 80% specificity (cut-off value) | Specificity for 80% sensitivity (cut-off value) | |
| Average NAWM CBF | |||
| Healthy vs primary NPSLE | 0.836 (0.0001) | 73% (1.01) | 65% (1.12) |
| Non-NPSLE vs primary NPSLE | 0.735 (0.002) | 55% (0.88) | 58 % (1.11) |
| Primary vs s Secondary NPSLE | 0.785 (0.001) | 65% (0.95) | 63 % (1.11) |
| Left SOC CBF | |||
| Healthy vs primary NPSLE | 0.854 (0.0001) | 68% (0.75) | 78% (0.77) |
| Non-NPSLE vs primary NPSLE | 0.803 (0.0001) | 65% (0.65) | 67% (0.77) |
| Primary vs secondary NPSLE | 0.813 (0.0001) | 65% (0.68) | 69% (0.77) |
| Right SOC CBF | |||
| Healthy vs primary NPSLE | 0.840 (0.0001) | 70% (0.68) | 61% (0.79) |
| Non-NPSLE vs primary NPSLE | 0.812 (0.0001) | 65% (0.64) | 63% (0.80) |
| Primary vs secondary NPSLE | 0.796 (0.001) | 67% (0.65) | 38% (0.80) |
AUC, area under the curve and associated P value; CBF, cerebral blood flow; NAWM, normal-appearing white matter; SOC, semioval centre.