Table 4

Healthcare costs by MBDA category*

MBDA scoren*Baseline 12 month costs, $
Median (IQR)
Incremental healthcare costs
compared with baseline, $
Median (IQR)†
All costs‡<30126910 257 (4587–25 421)−443 (−4194 to 4312)
30–44390412 480 (5504–28 227)−243 (−4990 to 6160)
>44488514 581 (5693–33 006)459 (−5320 to 10794)
Medical costs§<3012696804 (3601–16 504)−192 (−3425 to 3872)
30–4439048889 (4324–20 854)43 (−4255 to 5241)
>44488511 247 (4522–27 586)366 (−5078 to 9729)
  • *Analysis conducted among subgroup of patients with 1-year baseline and 1-year follow-up; n values are lower than main cohort because of the latter requirement.

  • †Calculated as the costs in the year following the first measurement of the MBDA score minus costs in the baseline year.

  • ‡Includes cost from inpatient, outpatient, nursing home, durable medical equipment, home health and part D drug.

  • §Excluded costs related to parenteral rheumatoid arthritis therapies (eg, intravenous biologics) that bill under Medicare part B.

  • MBDA, multibiomarker disease activity.