Table 5

Risk of pre-eclampsia and preterm birth in population controls, women (SLE) with inactive disease and women (SLE) with active disease. Logistic regression with adverse event as outcome*

Groupnn (%)OR (95 % CI)P value
Population controls498 849
 Pre-eclampsia15 132 (3.0)
 Preterm birth27 063 (5.5)
Inactive disease (LAI-P=0)85
 Pre-eclampsia4 (4.7)1.58 (0.58 to 4.31)0.37†
 Preterm birth11 (12.9)2.57 (1.37 to 4.85)0.003†
Active disease (LAI-P>0)63
 Pre-eclampsia9 (14.3)5.33 (2.63 to 10.79)<0.001†
3.38 (0.99 to 11.51)0.052‡
 Preterm birth21 (33.3)8.66 (5.13 to 14.62)<0.001†
3.36 (1.48 to 7.65)0.004‡
  • *Unadjusted analysis.

  • †Compared with population controls.

  • ‡Compared with inactive disease.

  • LAI-P, Lupus Activity Index in Pregnancy; SLE, systemic lupus erythematosus.