5 yearsn=62n=59p Value
DAS, mean±SD1.7±0.691.6±0.820.469
HAQ, mean±SD0.83±0.650.82±0.640.936
Swollen joint count, median (IQR)/mean±SD0.0 (0.0–1.0)/1.2±2.60.0 (0.0–2.0)/1.2±2.00.200
Tender joint count, median (IQR)/mean±SD1.0 (0.0–3.0)/2.1±2.61.0 (0.0–4.0)/2.2±2.70.818
ESR (mm/hour), median (IQR)11 (6.8–23)12 (5.5–19)0.517
VAS global health (mm), mean±SD31±2227±230.369
Total SHS, median (IQR)/mean±SD (observed)1.0 (0.0–4.9)/4.2±7.91.5 (0.0–3.9)/3.8±6.90.816
Total SHS, median (IQR)/mean±SD (after imputation)1.3 (0.19–4.0)/3.7±6.81.9 (0.0–4.0)/3.4±5.90.340
Erosive, n (%) (observed)13 (21)13 (22)0.828
Erosive, n (%) (after imputation)19 (23)16 (21)0.753
SHS progression, median (IQR)/mean±SD (observed)0.0 (0.0–1.0)/2.5±6.10.0 (0.0–1.0)/2.0±5.20.818
SHS progression, median (IQR)/mean±SD (after imputation)0.50 (0.0–1.7)/2.0±4.80.29 (0.0–1.5)/1.7±4.40.115
SHS progression ≥0.5, n (%) (observed)23 (37)23 (39)1.000
SHS progression ≥0.5, n (%) (after imputation)46 (55)37 (47)0.327
SHS progression ≥5, n (%) (observed)9 (15)7 (12)0.710
SHS progression ≥5, n (%) (after imputation)11 (13)9 (12)0.653
SHS progression ≥10, n (%) (observed)3 (5)2 (3)0.968
SHS progression ≥10, n (%) (after imputation)4 (5)2 (3)0.712
In remission, n (%)31 (50)29 (49)0.768
In drug-free remission, n (%)9 (15)12 (20)0.374
In ACR/EULAR Boolean remission, n (%)8 (13)13 (22)0.186
  • Erosive indicates ≥1 erosions.

  • ACR, American College of Rheumatology; DAS, Disease Activity Score; ESR, erythrocyte sedimentation rate; EULAR, European League Against Rheumatism; HAQ, Health Assessment Questionnaire; SHS, Sharp/van der Heijde Score; VAS, Visual Analogue Scale.