Scores for PsA (disease manifestations depicted in green colour are included, those depicted in red colour are not included in the respective score)
Biomarker of inflammation | Articular inflammation | Global and pain assessments | Non-articular inflammatory musculoskeletal manifestions | Mixture of inflammatory activity and outcome | Non-musculoskeletal manifestations of PsA | |||||||||
Laboratory (C-reactive protein/erythrocyte sedimentation rate) | Swollen joints | Tender joints | Joints VAS | Patient global VAS | Patient pain VAS | Physician global VAS | Enthesitis | Dactylitis | Axial | Function | Health-related quality of life | Skin | ||
Multidimen-sional | CPDAI | |||||||||||||
GRACE | ||||||||||||||
PASDAS | ||||||||||||||
MDA | ||||||||||||||
Unidimen-sional | DAPSA |
Calculations
Composite Psoriatic Disease Activity Index (CPDAI): Peripheral arthritis (TJC of 68 joints+SJC of 66 joints+HAQ), skin disease (PASI+DLQI), enthesitis (Leeds Enthesitis Index), dactylitis count, axial disease (BASDAI+ASQoL); each domain is scored 0–3 (for ‘no’, ‘mild’, ‘moderate’ and ‘severe’ involvement based on disease activity and impact measures) giving a total of 0–15, in which 0 represents no disease activity.
GRAppa Composite Exercise (GRACE) index: (1–arithmetic mean of eight variables)x10, the arithmetic mean is based on eight equally weighted variables TJC and SJC, HAQ, PtGA by VAS (1–10 cm), patient skin VAS (1–10 cm), patient joint VAS (1–10 cm), PASI (0–72), PsAQoL (0–20); the index provides a score of 0–10, where 0 is best and 10 is worst.
Psoriatic Arthritis Disease Activity Score (PASDAS): (((0.18√ PGA) + (0.159√ PtGA) – (0.253 x √ SF-36) + (0.101 x LN (SJC + 1)) + (0.048 x LN (TJC + 1)) + (0.23 x LN (LEI +1)) + (0.37 LN (tender dactylitis count + 1)) + (0.102 x LN (CRP + 1)) +2) x 1.5
Minimal Disease Activity (MDA): Fulfillment of five of seven criteria: TJC ≤1/68, SJC ≤1/66, PASI≤1 or BSA ≤3, enthesitis ≤1, PtGA (by VAS, 1–10 cm) ≤2 cm, pain VAS (1–10 cm) ≤1.5 cm, HAQ ≤0.5.
Disease Activity index for PSoriatic Arthritis (DAPSA): Sum of SJ66+TJ68+PtGA (in cm)+pain VAS (in cm)+CRP (mg/dL).