(B)
<60 years60–79 years≥80 years
Patients with SSc
n=454
General population
n=1 020 794
O/E ratio
(95% CI)
Patients with SSc
n=1473
General population
n=2 162 597
O/E ratio
(95% CI)
Patients with SSc
n=792
General population
n=3 311 866
O/E ratio
(95% CI)
Cardiovascular disease176 (38.8%)125 895 (12.3%)3.14 (2.80 to 3.53)576 (39.1%)524 385 (24.2%)1.61 (1.51 to 1.72)318 (40.1%)1 185 853 (35.8%)1.12 (1.03 to 1.22)
Respiratory disease94 (20.7%)22 248 (2.2%)9.50 (7.93 to 11.38)292 (19.8%)113 894 (5.3%)3.76 (3.40 to 4.17)120 (15.1%)268 580 (8.1%)1.87 (1.58 to 2.20)
Infectious disease56 (12.3%)23 135 (2.3%)5.44 (4.26 to 6.96)162 (11.0%)40 009 (1.8%)5.94 (5.14 to 6.88)85 (10.7%)65 882 (2.0%)5.39 (4.41 to 6.60)
Malignant neoplasm60 (13.2%)362 804 (35.5%)0.37 (0.29 to 0.47)135 (9.2%)881 509 (40.8%)0.22 (0.19 to 0.26)58 (7.3%)568 928 (17.2%)0.43 (0.33 to 0.55)
Gastrointestinal disease30 (6.6%)61 906 (6.1%)1.09 (0.77 to 1.54)95 (6.4%)102 975 (4.8%)1.35 (1.11 to 1.64)27 (3.4%)122 439 (3.7%)0.92 (0.64 to 1.34)
  • Unless specified otherwise, the values are numbers (%) of observations.

  • O/E, observed/expected; SSC, systemic sclerosis.