(A) Sex-adjusted and age-adjusted O/E ratios for the cause of death in SSc and (B) age-adjusted O/E ratios for the cause of death in SSc
| (A) | |||||||||
| Male | Female | Total | |||||||
| Patients with SSc n=562 | General population n=3 327 105 | O/E ratio (95% CI) | Patients with SSc n=2157 | General population n=3 168 152 | O/E ratio (95% CI) | Patients with SSc n=2719 | General population n=6 495 257 | O/E ratio (95% CI) | |
| Cardiovascular disease | 200 (35.6%) | 855 720 (25.7%) | 1.38 (1.24 to 1.55) | 870 (40.3%) | 980 413 (30.9%) | 1.30 (1.24 to 1.37) | 1070 (39.3%) | 1 836 133 (28.3%) | 1.39 (1.33 to 1.46) |
| Respiratory disease | 135 (24.0%) | 211 796 (6.4%) | 3.77 (3.28 to 4.37) | 371 (17.2%) | 192 326 (6.1%) | 2.83 (2.58 to 3.11) | 506 (18.6%) | 404 722 (6.2%) | 2.99 (2.76 to 3.23) |
| Infectious disease | 59 (10.5%) | 65 069 (1.9%) | 5.37 (4.22 to 6.83) | 244 (11.3%) | 63 957 (2.0%) | 5.60 (4.98 to 6.31) | 303 (11.1%) | 129 026 (2.0%) | 5.61 (5.04 to 6.24) |
| Malignant neoplasm | 75 (13.3%) | 1 077 631 (32.3%) | 0.41 (0.33 to 0.51) | 179 (11.9%) | 735 610 (23.2%) | 0.36 (0.31 to 0.41) | 254 (9.3%) | 1 813 241 (27.9%) | 0.33 (0.30 to 0.38) |
| Gastrointestinal disease | 28 (5.0%) | 154 423 (4.6%) | 1.07 (0.75 to 1.54) | 151 (7.0%) | 132 897 (4.2%) | 1.68 (1.44 to 1.96) | 179 (6.6%) | 287 320 (4.4%) | 1.49 (1.29 to 1.71) |