Rheumatoid arthritis (n=1326) | Psoriatic arthritis (n=728) | |||||
Depressed/anxious (n=573) | Not depressed/anxious (n=753) | p Value | Depressed/anxious (n=326) | Not depressed/anxious (n=402) | p Value | |
Age (years), mean (SD) | 53.5 (13.2) | 55.3 (13.8) | 0.02 | 46.9 (12.6) | 48.9 (12.4) | 0.03 |
Female, % | 75.1 | 62.3 | 0.01 | 59.7 | 44.1 | <0.001 |
Disease duration (years), median (25th, 75th percentile) | 0.27 (0.006, 5.3) | 0.27 (0.003, 5.0) | 0.72 | 0.95 (0.08, 6.4) | 0.70 (0.04, 7.1) | 0.78 |
Currently smoking n/total (%) | 185/572 (32.3) | 192/744 (25.8) | 0.009 | 109/323 (33.7) | 298/398 (25.1) | 0.01 |
Joint pain, mean (SD) | 51.8 (24.9) | 40.5 (24.9) | <0.001 | 52.6 (22.4) | 42.2 (22.9) | <0.001 |
32 tender joints, median (25th, 75th percentile) | 9 (4, 14) | 6 (3, 11) | <0.001 | 5 (2, 10) | 4 (2, 8) | 0.002 |
32 swollen joints, median (25th, 75th percentile) | 6 (3, 10) | 5 (3, 10) | 0.26 | 2 (1, 5) | 3 (1, 6) | 0.16 |
EGA, mean (SD) | 37.6 (19.0) | 35.4 (19.3) | 0.04 | 33.8 (16.3) | 31.1 (15.7) | 0.03 |
PGA, mean (SD) | 55.2 (24.3) | 42.5 (24.1) | <0.001 | 56.2 (22.1) | 44.6 (23.0) | 0.001 |
DAS28ESR, mean (SD) | 4.8 (1.3) | 4.5 (1.4) | <0.001 | 4.1 (1.3) | 3.8 (1.2) | 0.002 |
DAS28CRP, mean (SD) | 4.6 (1.2) | 4.3 (1.3) | <0.001 | 4.0 (1.1) | 3.7 (1.1) | 0.002 |
SDAI (25th, 75th percentile) | 22.4 (15.6, 32.3) | 19.2 (12.1, 30.5) | <0.001 | 16.5 (11.4, 23.3) | 13.9 (9.6, 21.0) | 0.001 |
CDAI (25th, 75th percentile) | 21.0 (14.2, 30.4) | 17.4 (10.9, 27.5) | <0.001 | 14.8 (10.6, 21.5) | 12.8 (8.7, 18.9) | 0.001 |
MHAQ (25th, 75th percentile) | 0.8 (0.4, 1.1) | 0.5 (0.1, 0.9) | <0.001 | 0.6 (0.4, 1.0) | 0.5 (0.1, 0.8) | <0.001 |
Modified DAPSA, median (25th, 75th percentile) | 27.4 (19.6, 38.0) | 22.2 (14.5, 34.1) | <0.001 | 21.1 (14.3, 28.2) | 17.5 (11.7, 24.7) | <0.001 |
ESR, mm/h, median (25th, 75th percentile) | 19 (11, 35) | 21 (11, 37) | 0.19 | 17 (7, 30) | 15 (8, 26) | 0.42 |
CRP, mg/L, median (25th, 75th percentile) | 8 (3, 21) | 8 (5, 23) | 0.29 | 7 (3, 20) | 6 (4, 155) | 0.70 |
Erosive disease at baseline, n/total (%) | 249/558 (44.6) | 317/731 (43.4) | 0.65 | 115/320 (35.9) | 144/385 (37.4) | 0.69 |
CDAI, Clinical Disease Activity Index; CRP, C reactive protein; DAPSA, Disease Activity Index for Psoriatic Arthritis; DAS28ESR, 28-joint Disease Activity Score; EGA, evaluator’s global assessment on a 0–100 Visual Analogue Scale (VAS) scale; ESR, erythrocyte sedimentation rate; MHAQ, Modified Health Assessment Questionnaire; PGA, patient’s global assessment on a 0–100 VAS scale; SDAI, Simplified Disease Activity Index.