Table 1

Demographics and baseline disease activity measures for patients with versus without baseline depression/anxiety according to the EQ-5D-3L criterion

Rheumatoid arthritis (n=1326)Psoriatic arthritis (n=728)
Depressed/anxious
(n=573)
Not depressed/anxious
(n=753)
p ValueDepressed/anxious (n=326)Not depressed/anxious
(n=402)
p Value
Age (years), mean (SD)53.5 (13.2)55.3 (13.8)0.0246.9 (12.6)48.9 (12.4)0.03
Female, %75.162.30.0159.744.1<0.001
Disease duration (years), median (25th, 75th percentile)0.27 (0.006, 5.3)0.27 (0.003, 5.0)0.720.95 (0.08, 6.4)0.70 (0.04, 7.1)0.78
Currently smoking n/total (%)185/572 (32.3)192/744 (25.8)0.009109/323 (33.7)298/398 (25.1)0.01
Joint pain, mean (SD)51.8 (24.9)40.5 (24.9)<0.00152.6 (22.4)42.2 (22.9)<0.001
32 tender joints, median (25th, 75th percentile)9 (4, 14)6 (3, 11)<0.0015 (2, 10)4 (2, 8)0.002
32 swollen joints, median (25th, 75th percentile)6 (3, 10)5 (3, 10)0.262 (1, 5)3 (1, 6)0.16
EGA, mean (SD)37.6 (19.0)35.4 (19.3)0.0433.8 (16.3)31.1 (15.7)0.03
PGA, mean (SD)55.2 (24.3)42.5 (24.1)<0.00156.2 (22.1)44.6 (23.0)0.001
DAS28ESR, mean (SD)4.8 (1.3)4.5 (1.4)<0.0014.1 (1.3)3.8 (1.2)0.002
DAS28CRP, mean (SD)4.6 (1.2)4.3 (1.3)<0.0014.0 (1.1)3.7 (1.1)0.002
SDAI (25th, 75th percentile)22.4 (15.6, 32.3)19.2 (12.1, 30.5)<0.00116.5 (11.4, 23.3)13.9 (9.6, 21.0)0.001
CDAI (25th, 75th percentile)21.0 (14.2, 30.4)17.4 (10.9, 27.5)<0.00114.8 (10.6, 21.5)12.8 (8.7, 18.9)0.001
MHAQ (25th, 75th percentile)0.8 (0.4, 1.1)0.5 (0.1, 0.9)<0.0010.6 (0.4, 1.0)0.5 (0.1, 0.8)<0.001
Modified DAPSA, median (25th, 75th percentile)27.4 (19.6, 38.0)22.2 (14.5, 34.1)<0.00121.1 (14.3, 28.2)17.5 (11.7, 24.7)<0.001
ESR, mm/h, median (25th, 75th percentile)19 (11, 35)21 (11, 37)0.1917 (7, 30)15 (8, 26)0.42
CRP, mg/L, median (25th, 75th percentile)8 (3, 21)8 (5, 23)0.297 (3, 20)6 (4, 155)0.70
Erosive disease at baseline, n/total (%)249/558 (44.6)317/731 (43.4)0.65115/320 (35.9)144/385 (37.4)0.69
  • CDAI, Clinical Disease Activity Index; CRP, C reactive protein; DAPSA, Disease Activity Index for Psoriatic Arthritis; DAS28ESR, 28-joint Disease Activity Score; EGA, evaluator’s global assessment on a 0–100 Visual Analogue Scale (VAS) scale; ESR, erythrocyte sedimentation rate; MHAQ, Modified Health Assessment Questionnaire; PGA, patient’s global assessment on a 0–100 VAS scale; SDAI, Simplified Disease Activity Index.