Subgroup | Relapse risk | p Value | OR (95% CI) | |
Treatment arm | W | 32/51 (63%) | <0.0001 | 5.96 (2.58 to 13.77) |
C | 13/59 (22%) | |||
ANCA specificity at diagnosis | PR3 | 28/57 (49%) | 0.13 | 1.82 (0.83 to 3.98) |
MPO | 17/49 (35%) | |||
ANCA testing at randomisation | Positive | 30/58 (51%) | 0.017 | 2.57 (1.16 to 5.68) |
Negative | 15/51 (29%) | |||
Disease | MPA | 22/58 (38%) | 0.5 | 0.77 (0.36 to 1.65) |
GPA | 23/52 (44%) |
AAV, ANCA-associated vasculitis; C, continuation subgroup; GPA, granulomatosis with polyangiitis; MPA, microscopic polyangiitis; MPO, myeloperoxidase; PR3, proteinase 3; W, withdrawal subgroup.