Table 3

Risk factors associated with AAV relapse

SubgroupRelapse riskp ValueOR (95% CI)
Treatment armW32/51 (63%)<0.00015.96 (2.58 to 13.77)
C13/59 (22%)
ANCA specificity at diagnosisPR328/57 (49%)0.131.82 (0.83 to 3.98)
MPO17/49 (35%)
ANCA testing at randomisationPositive30/58 (51%)0.0172.57 (1.16 to 5.68)
Negative15/51 (29%)
DiseaseMPA22/58 (38%)0.50.77 (0.36 to 1.65)
GPA23/52 (44%)
  • AAV, ANCA-associated vasculitis; C, continuation subgroup; GPA, granulomatosis with polyangiitis; MPA, microscopic polyangiitis; MPO, myeloperoxidase; PR3, proteinase 3; W, withdrawal subgroup.