Correlation between wrist MRI features and patient-reported outcomes
Baseline | 1-year follow-up | 5 years follow-up | Δ Baseline – 1-year follow-up | Δ Baseline – 5 years follow-up | |
HAQ | |||||
MRI synovitis | 0.25*** | 0.09 | 0.13 | 0.21** | 0.22* |
MRI tenosynovitis | 0.18*** | −0.02 | 0.13 | 0.24** | 0.19 |
MRI osteitis | 0.12 | 0.21** | 0.18 | 0.16* | 0.32** |
MRI erosion | 0.03 | 0.08 | 0.16 | 0.00 | −0.07 |
MRI JSN | −0.05 | 0.19* | 0.13 | −0.08 | −0.15 |
MRI combined inflammation | 0.21** | 0.08 | 0.16 | 0.26** | 0.25* |
MRI combined damage | 0.02 | 0.13 | 0.21* | −0.02 | −0.09 |
VAS-PtGlobal | |||||
MRI synovitis | 0.09 | −0.01 | 0.02 | 0.22** | 0.32** |
MRI tenosynovitis | −0.01 | −0.03 | 0.15 | 0.13 | 0.17 |
MRI osteitis | 0.12 | 0.09 | −0.02 | 0.25** | 0.24* |
MRI erosion | −0.06 | 0.03 | 0.09 | 0.05 | −0.09 |
MRI JSN | 0.02 | 0.05 | 0.09 | 0.02 | −0.16 |
MRI combined inflammation | 0.07 | 0.03 | 0.04 | 0.24** | 0.30** |
MRI combined damage | −0.03 | 0.04 | 0.16 | 0.06 | −0.14 |
VAS-pain | |||||
MRI synovitis | 0.18* | 0.03 | −0.02 | 0.28*** | 0.45*** |
MRI tenosynovitis | 0.04 | −0.03 | 0.18 | 0.16* | 0.29** |
MRI osteitis | 0.08 | 0.14 | −0.06 | 0.22** | 0.29** |
MRI erosion | −0.02 | 0.01 | 0.04 | 0.03 | −0.18 |
MRI JSN | 0.05 | 0.07 | 0.03 | 0.01 | −0.16 |
MRI combined inflammation | 0.11 | 0.08 | 0.01 | 0.28*** | 0.40*** |
MRI combined damage | 0.00 | 0.03 | 0.08 | 0.03 | −0.18 |
Associations for status and change scores by Spearman’s correlations. Statistically significant correlations are written in bold and are interpreted as follows: *p<0.05, **p<0.01, ***p<0.001.
Δ, change; HAQ, health assessment questionnaire; JSN, joint space narrowing; PtGlobal, patient global; VAS, visual analogue scale.