Table 2

Frequency of NCF1-339 genotype groups

Study populationsT-type genotypes
Frequency (n)
C-type genotypes
Frequency (n)
p ValueOdds ratio (95% CI)
Discovery population
 Patients with SLE0.18 (101)0.82 (469)5.7×10−12 3.15 (2.26 to 4.39)
 EIRA controls0.06 (65)0.94 (951)
Replication population
 Karolinska patients with SLE0.16 (64)0.84 (339)2.5×10−8 5.79 (2.91 to 11.55)
 Karolinska controls0.03 (9)0.97 (276)
Meta-analysis
 Patients with SLE0.17 (165)0.83 (808)1.8×10−18 3.65 (2.70 to 4.91)
 Controls0.06 (74)0.94 (1227)
  • EIRA, epidemiological investigation of rheumatoid arthritis; SLE, systemic lupus erythematosus.