Table 1

Allele frequencies of NCF1-339

Study populationsT allele
Frequency (n)
C allele
Frequency (n)
p ValueOR (95% CI)
Discovery population
 Patients with SLE0.11 (132)0.89 (1074)3.2×10−12 2.63 (2.00 to 3.45)
 EIRA controls0.04 (96)0.96 (2052)
Replication population
 Karolinska SLE0.10 (88)0.90 (764)1.3×10−9 4.59 (2.63 to 8.02)
 Karolinska controls0.02 (15)0.98 (598)
Meta-analysis
 Patients with SLE0.11 (220)0.89 (1838)7.0×10−20 3.03 (2.37 to 3.86)
 Controls0.04 (111)0.96 (2650)
  • EIRA, epidemiological investigation of rheumatoid arthritis; SLE, systemic lupus erythematosus.