Demographic and baseline characteristics of patients
| CS n=199 | Celecoxib n=199 | Placebo n=205 | |
| Age (years) | |||
| Mean (SD) | 65.5 (8.0) | 65.5 (7.8) | 64.9 (8.0) |
| Sex, n (%) | |||
| Female | 156 (78.4) | 160 (80.4) | 152 (74.1) |
| Height (cm) | |||
| Mean (SD) | 163.3 (8.8) | 162.8 (9.4) | 164.6 (9.5) |
| Weight (kg) | |||
| Mean (SD) | 80.4 (14.1) | 78.4 (13.9) | 82.9 (14.7) |
| BMI (kg/m2) | |||
| Mean (SD) | 30.2 (4.7) | 29.5 (4.4) | 30.6 (5.0) |
| Time from diagnosis of knee OA (months) | |||
| Mean (SD) | 72.3 (69.2) | 64.4 (63.4) | 69.2 (72.5) |
| KL grade, n (%) | |||
| Grade 1 | 48 (24.1) | 46 (23.1) | 53 (25.9) |
| Grade 2 | 100 (50.3) | 101 (50.8) | 101 (49.3) |
| Grade 3 | 50 (25.1) | 52 (26.1) | 51 (24.9) |
| Grade 4 | 1 (0.5) | 0 (0.0) | 0 (0.0) |
| Duration of regular pain (months) | |||
| Mean (SD) | 41.7 (60.3) | 39.9 (56.5) | 47.8 (68.1) |
| Target knee (the most symptomatic) | |||
| Left, n (%) | 85 (42.7) | 95 (47.7) | 92 (44.9) |
| Target knee pain (VAS, mm) | |||
| Mean (SD) | 70.9 (9.8) | 69.7 (10.2) | 70.0 (10.3) |
| Lequesne’s Algo-Functional Index (LI total score) | |||
| Mean (SD) | 11.8 (2.9) | 11.6 (2.9) | 11.8 (3.1) |
BMI, body mass index; KL, Kellgren-Lawrence; LI, Lequesne Index; OA, osteoarthritis; VAS, Visual Analogue Scale.