Table 3

Pooled HRs (95% CI) for incident RA according to cumulative AHEI-2010 quartile in Nurses' Health Study (NHS, 1984–2012) and NHSII (1991–2013) stratified by age before or after 55 years

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  • HRs were calculated by using time-varying Cox proportional hazards models.

  • *p for trend was derived from tests of linear trend across categories of AHEI scores by treating the median value of each category as a continuous variable.

  • †Adjustment for age, cohort, smoking (never, past, current 1–14 cigarettes/day, current ≥15 cigarettes/day), age at menarche (<12, 12, >12 years), parity and breast feeding (nulliparous, parous/no breast feeding, parous/1–12 months breast feeding, parous/ >12 months breast feeding), hormone use (premenopausal, postmenopausal with never use, current use and past use) and total energy (quintiles).

  • ‡Additional adjustment for BMI (<20, 20–22.9, 23–24.9, 25–29.9, ≥30 kg/m2).

  • AHEI-2010, 2010 Alternative Healthy Eating Index; BMI, body mass index; RA, rheumatoid arthritis.