Axial spondyloarthritis Univariate Final model
HR p HR p
Gender, women versus men2.29 (1.22 to 4.29) 0.01 1.85 (0.81 to 4.25)0.15
Age, years0.98 (0.96 to 1.02)0.150.99 (0.95 to 1.03)0.6
Methotrexate use, no versus yes1.36 (0.68 to 2.86)0.4
Patient’s global score, mm1.02 (1.01 to 1.03) 0.003 1.02 (1.01 to 1.04)0.009
BASDAI1.02 (1.01 to 1.04) 0.003
ASDAS1.09 (0.76 to 1.56)0.6
CRP, mg/L0.92 (0.84 to 1.01) 0.08 0.90 (0.81 to 1.00)0.04
Longer CT-P13 interval, weeks0.69 (0.54 to 0.88) 0.002
Higher CT-P13 dose, mg/kg1.66 (1.22 to 2.26) 0.001 1.63 (1.06 to 2.51)0.03
INX start year 2000–2007 versus 2008–20150.32 (0.16 to 0.65) 0.002
Number of comorbidities0.67 (0.34 to 1.39)0.3
  • Results from univariable and multivariable Cox regression analyses stratified by diagnosis.

  • Cox regression analyses stratified by diagnosis. Numbers are HR (95% CI). p Values <0.1 are marked with bold and the corresponding variables were included in multivariable analysis. Age and gender remained in the model irrespective of p value.

  • ASDAS, Ankylosing Spondylitis Disease Activity Score; BASDAI, Bath Ankylosing Spondylitis Disease Activity Index; CRP, C reactive protein; DAS28, 28 Joint Disease Activity Score.