Table 1.

Estimated association between vitamin D levels and odds of organ-specific lupus disease activity, adjusting for age, race, sex, calendar year, prednisone use and plaquenil use

Vitamin D Level (ng/mL)Immunologic Disease ActivitySkin Disease ActivityRenal Disease Activity
OR (95% CI)P-valueOR (95% CI)P-valueOR (95% CI)P-value
<10 (n=163)1.0 (0.7, 1.5)0.881.4 (1.0, 2.1)0.0493.1 (2.0, 4.9)<0.0001
10–20 (n=1039)1.0 (0.9, 1.1)0.930.9 (0.8, 1.1)0.412.2 (1.5, 3.1)<0.0001
20–30 (n=2760)1.0 (0.9, 1.1)0.971.0 (0.9, 1.2)0.531.6 (1.2, 2.0)0.0008
30–40 (n=3959)1.0 (0.9, 1.1)0.781.1 (1.0, 1.2)0.131.2 (0.9, 1.5)0.23
40–50 (n=3578)1.0 (Ref Grp)1.0 (Ref Grp)1.0 (Ref Grp)
50–60 (n=2308)1.0 (0.9, 1.1)0.781.1 (0.9, 1.3)0.191.0 (0.7, 1.3)0.91
60–70 (n=929)1.0 (0.9, 1.2)0.981.0 (0.8, 1.3)0.740.8 (0.5, 1.3)0.33
70–80 (n=504)1.1 (0.8, 1.2)0.921.3 (1.0, 1.7)0.0720.8 (0.4, 1.4)0.41
80+ (n=356)(1.1 (0.9, 1.4)0.421.4 (1.0, 1.9)0.0720.6 (0.3, 1.6)0.32