Table 1.

Comparison of anxious vs non-anxious and depressive vs non-depressive patients

HADS-A <8HADS-A ≥8pHADS-D<8HADS-D ≥8p
N967710271
Gender (M%)18.8%9.1%0.07318.6%8.5%0.061
Age at diagnosis, mean ± SD (years)44.5±13.245.4±12.70.60642.3±12.748.5±12.50.009
Age at 1st bMARD, mean ± SD (years)53.6±11.154.9±10.00.42252.4±10.356.8±10.60.008
HADS-A, mean ± SD4.99±3.510.2±4.04<0.001
HADS-D, mean ± SD4.1±3.69.6±3.7<0.001
HAQ, mean ± SD0.75±0.61.26±0.6<0.0010.7±0.51.3±0.6<0.001
DAS28 ESR, mean ± SD3.1±1.14.0±1.4<0.0013.1±1.04.1±1.5<0.001
28 TJC, mean ± SD1.83±3.34.95±5.8<0.0011.92±3.15.08±6.1<0.001
28 SJC, mean ± SD1.02±1.71.86±2.70.0420.97±1.52.00±2.90.020
PGA (VAS), mean ± SD28.46±23.246.3±24.1<0.00128.9±23.0347.3±24.2<0.001
Patients' pain assessment (VAS), mean ± SD28.4±22.546.4±26.2<0.00128.8±22.447.3±26.5<0.001
PhGA (VAS), mean ± SD15.9±13.923.8±20.60.02214.4±12.726.5±20.8<0.001
ESR (mm/H), mean ± SD26.42±19.628.43±21.20.51325.3±18.430.2±22.60.190
CRP (mg/L), mean ± SD6.9±10.99.3±23.50.7716.1±8.910.6±25.30.808
CDAI, mean ± SD7.3±7.113.8±11.2<0.0017.2±6.414.5±11.7<0.001
SDAI, mean ± SD8.2±7.414.96±12.4<0.0017.97±6.715.8±12.97<0.001
FACIT-F, mean ± SD39.8±7.529.3±7.7<0.00139.1±7.829.4±8.2<0.001
EQ5D, mean ± SD0.43±0.170.28±0.20<0.0010.44±0.170.26±0.19<0.001