| Case | 1 | 2 | 3 | 4 | 5 | 6 | 7 |
|---|---|---|---|---|---|---|---|
| Symptoms | Polyarthralgias Arthritis | General pain | Polyarthralgias | Arthromyalgias | Polyarthralgias | Hand pain and deformity of 2nd PIPs | Left foot edema |
| 4th interphalangeal joint | Dry eye and dry mouth | Back pain | Fatigue | Back pain | |||
| Inflammatory markers + | Fever | Fatigue, oral aphthosis | |||||
| Anti-TNF-a | |||||||
| Gender | ♀ | ♀ | ♀ | ♂ | ♀ | ♀ | ♀ |
| Age | 45 | 47 | 37 | 48 | 39 | 56 | 55 |
| Hemogram/Renal/liver function | N | N | N | N | N | N | N |
| RF/ACPA | (–) | (–) | (–) | (–) | (–) | (–) | (–) |
| ANA (IFI)/ENAs | +1/160/– | +1/160/– | +1/320/– | +1/160/– | +1/160/– | +1/320/– | +1/80/– |
| C3, C4 | NP | N | NP | NP | NP | NP | NP |
| Schirmer/Ss | NP | N | NP | NP | NP | NP | NP |
| CRP/ESR | N | N | 21/17 | N | N | N | N |
| Comorbidities | Type 2 DM | Graves Basedow | Hand angioedema | PsA | Graves Basedow | Dyslipidemia | No |
| RX /MRI | CPPD | Degeneration of left TMC and dorsal spine | L4-L5, L5-S1 Retrolistesis | Mild degenerative signs in PIP and TMCs | Synovial fluid in talo-navicular and tarsal joints | ||
| Axial/joint | Degenerative axial and joint signs | C5-C6-C7 Protrusions | |||||
| Diagnosis | OA | OA | OA | PsA | Fibromyalgia | OA | Resolved foot arthritis |
| CPPD | Discopathy | Chronic fatigue | |||||
NP: not performed, N: normal, OA: osteoarthritis, PsA: psoriatic arthritis, CPPD: chondrocalcinosis.