MOBILITY | TARGET | |||
---|---|---|---|---|
Sarilumab 200 mg q2w + MTX | Sarilumab 200 mg q2w + csDMARDs | |||
Gene | P value | Fold reductiona | P value | Fold reductiona |
THBD | 6.3×10–7 | 0.67 | 3.9×10–6 | 0.58 |
PECAM-1 | 1.6 × 10–9 | 0.78 | 2.1×10–4 | 0.78 |
vWF | 1.3×10–10 | 0.58 | 0.55 | 0.91 |
aFold reduction vs placebo.