Table. Radiographic progression at week 88
| Outcome | Flare Patients | Non-flare Patients | P-value* |
|---|---|---|---|
| Flare defined as loss of LDA and DAS28 change of 0.6 | |||
| mTSS >0 | 43/271 (15.9) | 31/260 (11.9) | 0.2109 |
| mTSS ≥0.5 | 38/271 (14.0) | 24/260 (9.2) | 0.1045 |
| mTSS ≥2.3 | 20/271 (7.4) | 10/260 (3.8) | 0.0914 |
| mTSS ≥5.0 | 9/271 (3.3) | 2/260 (0.8) | 0.0633 |
| Flare defined as loss of LDA | |||
| mTSS >0 | 44/280 (15.7) | 30/251 (12.0) | 0.2586 |
| mTSS ≥0.5 | 39/280 (13.9) | 23/251 (9.2) | 0.1043 |
| mTSS ≥2.3 | 20/280 (7.1) | 10/251 (4.0) | 0.1338 |
| mTSS ≥5.0 | 9/280 (3.2) | 2/251 (0.8) | 0.0670 |
| Flare defined as relapse | |||
| mTSS >0 | 35/181 (19.3) | 39/350 (11.1) | 0.0119 |
| mTSS ≥0.5 | 31/181 (17.1) | 31/350 (8.9) | 0.0065 |
| mTSS ≥2.3 | 19/181 (10.5) | 11/350 (3.1) | 0.0011 |
| mTSS ≥5.0 | 9/181 (5.0) | 2/350 (0.6) | 0.0015 |
*Fisher's exact test. Overall treatment group. Values are n/N (%).