Table 1.

Hazard Ratio and 95% CI for Serious Infection in the ALL BARI RA Analysis Set

Clinical Factor	Univariate	Multivariate

	HR [95% CI]	HR [95% CI]

Line of therapy (bDMARD-IR vs. csDMARD-IR)	1.6 [1.1, 2.3]	1.5 [1.0, 2.3]
Age (65+ vs. 18–64 yrs)^a	2.2 [1.6, 3.2]	2.5 [1.8, 3.6]
Region (Asia [excluding Japan] vs. US/Canada)	2.4 [1.3, 4.4]	2.7 [1.4, 5.2]
BMI (kg/m²) (vs. normal [18–24])^a
Underweight (<18)	3.4 [1.7, 7.0]	3.1 [1.5, 6.4]
Overweight (25–29)	1.6 [1.0, 2.4]	1.8 [1.1, 2.7]
Obese (≥30)	1.4 [0.9, 2.2]	1.8 [1.1, 2.9]
RA duration (10+ vs. 0–4 yrs)^a	1.7 [1.1, 2.6]	–
DAS28-hsCRP (for every one unit increase)^a	1.1 [1.0, 1.3]	–
HAQ-DI (≥1.5 vs. <1.5)^a	1.5 [1.1, 2.1]	–
Corticosteroid dose (mg/day)^a
0.1–4.9 vs. none	2.2 [1.3, 3.7]	2.3 [1.4, 3.9]
5+ vs. none	1.7 [1.2, 2.5]	1.9 [1.3, 2.7]