ECG characteristics of pts with RA treated with TOFA
| Baseline | After 12 months | |
|---|---|---|
| 12-lead ECG | ||
| Heart rate, bpm | 71 [64;81] | 69 [61;78] |
| PQ, ms | 133 [126;131] | 150 [130;160]* |
| QRS, ms | 83 [79;89] | 84 [80;91] |
| QTc, ms | 421 [406;434] | 410 [398;420] |
| 24 h ECG | ||
| Heart rate, bpm | 78 [70;84] | 74 [65;80]* |
| QRS, ms | 82 [73;91] | 85 [73;92]* |
| QTc, ms | 409 [402;425] | 415 [406;427]* |
| QTc night, ms | 414 [400;434] | 420 [408;437]* |
| VPB pts, n (%) | 18 (66) | 22 (78) |
| Ventricular premature beats, n | 14 [7;50] | 280 [15;3423]* |
Data are presented in median values and IR (unless otherwise noted), *p<0,05 before and after TOFA treatment (nonparametric paired Wilcoxon test).