Healthy controls (N=43) | ||||
---|---|---|---|---|
Dkk-1 pmol/l | 25,92±11,26† | |||
Sclerostin pmol/l | 33,11±16,85 | |||
PsA patients (N=28) | ||||
Baseline values (Mean ± SD) | month 1 | month 3 | month 6 | |
DAS28 | 3,97±1,30 | 3,78±1,21 | 3,57±1,58 | 3,41±1,55 |
P1NP ng/ml | 43,5±14,5 | -0,31±12,91 | -0,81±11,97 | 0,96±14,87 |
CTX ng/ml | 0,25±0,16 | 0,02±0,14 | 0,04±0,20 | 0,08±0,27 |
Dkk-1 pmol/l | 20,0±13,64 | -1,45±7,89 | -1,38±9,49 | 2,90±7,45* |
Sclerostin pmol/l | 30,9±12,02 | -0,76±8,39 | 3,09±7,54* | 3,03±7,77* |
*p<0,05 vs baseline, †p<0,05 vs Dkk-1 of the PsA group at baseline, month 1 and month 3.