The association of herpes zoster and all infections with incident giant cell arteritis stratified by time period prior to index date
| Herpes zoster infection | Any infection | |||
|---|---|---|---|---|
| Adjusted IRR (95% CI)* | p Value | Adjusted IRR (95% CI)* | p Value | |
| <1 year† | 1.32 (0.95 to 1.82) | 0.10 | 1.66 (1.54 to 1.79) | <0.01 |
| 1–2 years | 1.11 (0.79 to 1.56) | 0.55 | 1.32 (1.22 to 1.43) | <0.01 |
| 2–3 years | 1.00 (0.70 to 1.43) | 0.99 | 1.19 (1.09 to 1.29) | <0.01 |
| 3–4 years | 0.92 (0.63 to 1.36) | 0.69 | 1.19 (1.09 to 1.30) | <0.01 |
| 4–5 years | 1.15 (0.77 to 1.70) | 0.49 | 1.14 (1.05 to 1.25) | <0.01 |
| 5–10 years | 1.36 (1.14 to 1.64) | <0.01 | 1.26 (1.17 to 1.35) | <0.01 |
| >10 years | 1.18 (0.99 to 1.42) | 0.07 | 1.22 (1.13 to 1.32) | <0.01 |
*Adjusted for Charlson Comorbidity Index, alcohol use, smoking history, prior use of immunosuppressive therapies and prior use of oral glucocorticoids.
†Including 6 months prior to index date.
IRR, incident rate ratio.