Table 1

Patient demographics and baseline clinical characteristics

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  • *The upper limit of normal for CRP (high sensitivity) was 3 mg/L.

  • †One patient did not receive methotrexate (not identified until after randomisation), and this was considered a protocol violation.

  • ACPA, anticitrullinated protein antibody; CRP, C reactive protein; DAS28, Disease Activity Score 28; eow, every other week; ESR, erythrocyte sedimentation rate; HAQ DI, Health Assessment Questionnaire Disability Index; MBDA, multibiomarker disease activity; RA, rheumatoid arthritis; SD, standard deviation; ULN, upper limit of normal.