Cases N=4559 | Controls N=22 795 | p Value | |
---|---|---|---|
Age at index date, years | 74 (9) | 73 (10) | N/A* |
Female sex, % | 71% | 71% | N/A* |
Duration of follow-up before index date, years | 6.4 (4.6) | 6.5 (4.5) | 0.35 |
Charlson Comorbidity Index | 1 (0, 2) | 0 (0, 2) | <0.01 |
Alcohol use, % | 67% | 66% | 0.27 |
Tobacco use, % | 51% | 43% | <0.01 |
Prior use of glucocorticoid, % | 28% | 16% | <0.01 |
No. of prescriptions†, median (IQR) | 3 (1, 10) | 3 (1, 9) | <0.01 |
Time since last prescription (years)†, median (IQR) | 1.4 (0.6, 4.2) | 2.2 (0.8, 5.2) | <0.01 |
Prior use of immunosuppressive therapy, % | 3% | 2% | <0.01 |
No. of prescriptions†, median (IQR) | 19 (7, 51) | 22 (6, 56) | 0.98 |
Time since last prescription (years)†, median (IQR) | 0.8 (0.6, 3.7) | 0.7 (0.5, 4.7) | 0.14 |
Prior zoster vaccination, % | 0.6% | 0.4% | 0.09 |
Time since last vaccination (months)†, median (IQR) | 4 (2, 9) | 5 (2, 9) | 0.78 |
Data expressed as mean (SD) or percentage.
*Controls were age-matched and sex-matched to cases.
†Among patients who received a prescription.