Association between DMARDs and statins and incident diabetes in patients without cardiovascular disease (N=11,134; incident diabetes N=837 (7.8%))
| Adjusted HR* (95% CI) | p Value | |
|---|---|---|
| Statins | 2.31 (1.86 to 2.87) | <0.001 |
| Glucocorticoids | 1.50 (1.22 to 1.85) | <0.001 |
| HCQ | 0.62 (0.47 to 0.81) | 0.001 |
| DMARD groups | ||
| MTX monotherapy (referent) | 1.0 | – |
| Any abatacept | 0.24 (0.10 to 0.76) | 0.015 |
| Any other DMARD with MTX | 0.83 (0.62 to 1.10) | 0.203 |
| Other or no DMARDs | 1.08 (0.84 to 2.88) | 0.561 |
*Adjusted for age, sex, disease duration, socioeconomic status (employment and income), ethnicity, smoking, hypertension, comorbidity index, BMI, HAQ score, NSAID usage and year of entry.
BMI, body mass index; DMARDs, disease-modifying antirheumatic drugs; HAQ, health assessment questionnaire; HCQ, hydroxychloroquine; MTX, methotrexate; NSAID, non-steroidal anti-inflammatory drug.