Table 3

Demographic characteristics and prevalence of comorbidities of allopurinol episodes with atrial fibrillation

 Episodes with atrial fibrillation
No atrial fibrillation NE=7878Not on allopurinol NE=565On allopurinol NE=801p Value
Age, mean (SD)78.2 (7.2)78.0 (7.3)78.4 (7.1)0.42
Gender, N (%)0.65
 Male3430 (43.5)240 (42.5)350 (43.7)
 Female4448 (56.5)325 (57.5)451 (56.3)
Race, N (%)0.012
 White5546 (70.4)412 (72.9)637 (79.5)
 Black1254 (15.9)83 (14.7)97 (12.1)
 Others1078 (13.7)70 (12.4)67 (8.4)
Charlson–Romano comorbidity score, mean (SD)4.89 (3.77)5.16 (3.55)5.64 (3.79)0.02
 Diabetes3847 (48.8)280 (49.6)431 (53.8)0.12
 Hypertension7356 (93.4)524 (92.7)757 (94.5)0.18
 CVD1737 (22.1)112 (19.8)191 (23.9)0.08
 PVD2197 (27.9)148 (32.6)258 (32.2)0.89
  • Bold indicates statistically significant associations with a p-value of <0.05.

  • CVD, cerebrovascular disease; NE, number of episodes; PVD, peripheral vascular disease.