Table 4

Associations of baseline infrapatellar fat pat (IPFP) signal intensity alteration with baseline and changes in knee cartilage volume

 UnivariableMultivariable*
β (95% CI)β (95% CI)
Baseline cartilage volume
 Medial tibial87.3 (37.0 to 137.6)1.6 (−38.6 to 42.0)
 Lateral tibial65.6 (6.8 to 124.4)−25.5 (−73.9 to 22.9)
 Patellar13.9 (−63.9 to 91.7)117.1 (186.1 to48.2)
Change in cartilage volume
 Medial tibial−0.3 (−1.0 to 0.3)−0.1 (−0.8 to 0.6)
 Lateral tibial−0.5 (−1.0 to 0.5)0.5 (1.3 to0.2)
 Patellar−0.1 (−0.8 to 0.5)−0.1 (−0.9 to 0.7)
  • N=874 at baseline and n=357 at follow-up. Dependent variables: knee cartilage volume (mm3) or change in knee cartilage volume per annum (%); independent variables: IPFP signal intensity alteration (per grade). Significant associations are shown in bold.

  • *Adjusted for age, sex, body mass index, radiographic osteoarthritis and tibial bone area.