Table 3

Associations of baseline infrapatellar fat pat (IPFP) signal intensity alteration with baseline and changes in bone marrow lesions

 UnivariableMultivariable*
OR (95% CI)OR (95% CI)
Baseline bone marrow lesions
 Any bone marrow lesions1.72 (1.44 to 2.04)1.70 (1.41 to 2.05)
 Medial tibiofemoral1.42 (1.18 to 1.71)1.40 (1.14 to 1.71)
 Lateral tibiofemoral1.82 (1.50 to 2.22)1.81 (1.46 to 2.24)
 Patellar1.24 (1.00 to 1.52)1.30 (1.04 to 1.63)
Increases in bone marrow lesions
 Any bone marrow lesions1.76 (1.34 to 2.32)1.74 (1.30 to 2.34)
 Medial tibiofemoral1.66 (1.21 to 2.29)1.56 (1.11 to 2.19)
 Lateral tibiofemoral1.80 (1.33 to 2.44)1.75 (1.26 to 2.42)
 Patellar1.45 (1.06 to 2.00)1.52 (1.09 to 2.13)
  • N=874 at baseline and n=374 at follow-up. Dependent variables: baseline bone marrow lesions or increases in bone marrow lesions (yes vs no); independent variables: IPFP signal intensity alteration (per grade). Significant associations are shown in bold. *Adjusted for age, sex, body mass index and radiographic osteoarthritis.