Table 2

Associations of baseline infrapatellar fat pat (IPFP) signal intensity alteration with baseline and changes in knee cartilage defects

 UnivariableMultivariable*
OR (95% CI)OR (95% CI)
Baseline cartilage defects
 Medial tibiofemoral1.42 (1.18 to 1.71)1.40 (1.13 to 1.72)
 Lateral tibiofemoral1.67 (1.38 to 2.01)1.58 (1.28 to 1.95)
 Patellar1.49 (1.25 to 1.76)1.56 (1.29 to 1.88)
Increase in knee cartilage defects
 Medial tibiofemoral1.49 (1.16 to 1.93)1.48 (1.12 to 1.95)
 Lateral tibiofemoral1.61 (1.24 to 2.10)1.50 (1.14 to 1.97)
 Patellar1.14 (0.86 to 1.51)1.18 (0.87 to 1.59)
  • N=874 at baseline and n=357 at follow-up. Dependent variables: baseline cartilage defects or increases in knee cartilage defects (yes vs no); independent variables: IPFP signal intensity alteration (per grade). Significant associations are shown in bold.

  • *Adjusted for age, sex, body mass index and radiographic osteoarthritis.