Table 4

Predictors for any cardiovascular event—Cox regression analysis with age as time scale (n=1091, 100 events)

Model 1*Model 2†Multivariate model‡
VariableRR (95% CI)p ValueRR (95% CI)p ValueRR (95% CI)p Value
Smoker: ever1.16 (0.74 to 1.83)0.521.12 (1.71 to 1.78)0.62
Hypertension1.75 (1.16 to 2.63)0.0081.71 (1.11 to 2.64)0.02
Diabetes2.83 (1.74 to 4.58)<0.00012.53 (1.54 to 4.16)0.0002
High cholesterol1.13 (0.74 to 1.71)0.58
High triglyceride1.64 (1.06 to 2.52)0.031.32 (0.84 to 2.07)0.23
Duration of psoriasis1.01 (0.99 to 1.02)0.451.00 (0.99 to 1.02)0.67
Tender joint count
1–7 vs 01.73 (1.08 to 2.76)0.021.69 (1.05 to 2.73)0.03
>7 vs 02.27 (1.33 to 3.88)0.0031.88 (1.08 to 3.27)0.03
Swollen joint count
 1–7 vs 01.26 (0.82 to 1.95)0.291.16 (0.74 to 1.80)0.52
 >71.71 (0.95 to 3.08)0.081.50 (0.82 to 2.74)0.19
Enthesitis count1.18 (0.90 to 1.54)0.231.18 (0.90 to 1.55)0.23
Dactylitis count1.21 (1.09 to 1.33)0.00031.19 (1.07 to 1.32)0.0011.18 (1.06 to 1.32)0.003
Damaged joint count
 1–9 vs 01.56 (0.93 to 2.63)0.091.55 (0.90 to 2.66)0.11
 10–19 vs 01.42 (0.74 to 2.71)0.291.37 (0.70 to 2.66)0.34
 ≥20 vs 01.20 (0.61 to 2.37)0.601.36 (0.67 to 2.72)0.39
PASI
 10–19 vs <101.24 (0.56 to 2.74)0.591.09 (0.48 to 2.43)0.83
 >19 vs <101.28 (0.39 to 4.13)0.681.22 (0.38 to 3.96)0.84
Urate (log µmol/L)1.27 (0.72 to 2.26)0.411.11 (0.65 to 1.87)0.71
ESR0.0060.010.03
Men1.06 (0.82 to 1.35)1.03 (0.79 to 1.32)0.98 (0.76 to 1.26)
Women1.83 (1.19 to 2.82)1.73 (1.12 to 2.67)1.70 (1.10 to 2.62)
Leucocytes (log ×109/L)1.43 (0.69 to 2.95)0.341.30 (0.61 to 2.78)0.50
Neutrophils (log ×109/L)1.21 (0.75 to 1.95)0.431.18 (0.73 to 1.91)0.49
HAQ
 0.1–0.5 vs 00.89 (0.41 to 1.91)0.760.83 (0.38 to 1.78)0.63
 >0.5 vs 01.43 (0.76 to 2.71)0.271.13 (0.59 to 2.16)0.71
SF-36 PCS
 31–45 vs <300.91 (0.51 to 1.62)0.741.07 (0.69 to 1.93)0.82
>45 vs <300.35 (0.17 to 0.72)0.0040.45 (0.22 to 0.95)0.035
Medication use
 Anti TNF vs none1.07 (0.56 to 2.03)0.841.08 (0.55 to 2.09)0.82
MTX vs none2.64 (1.19 to 5.85)0.022.64 (1.16 to 6.04)0.02
 Other DMARDs vs none0.90 (0.52 to 1.56)0.711.04 (0.59 to 1.83)0.89
Oral corticosteroids1.92 (0.77 to 4.77)0.161.68 (0.66 to 4.23)0.27
Use of NSAIDs0.95 (0.64 to 1.44)0.820.93 (0.62 to 1.41)0.74
  • Bolded items are statistically significant.

  • *Each model included a single predictor, sex and PsA duration.

  • †Each model included the predictor on the respective row with sex, PsA duration, hypertension, diabetes, smoking and high triglyceride.

  • ‡The full model included sex, PsA duration, hypertension, diabetes, smoking and high triglyceride.

  • DMARD, disease-modifying antirheumatic drug; ESR, erythrocyte sedimentation rate; HAQ, health assessment questionnaire; MTX, methotrexate; NSAIDs, non-steroidal anti-inflammatory drugs; PASI, psoriasis area and severity index; PsA, psoriatic arthritis; RR, Relative Risk; TNF, tumour necrosis factor.