| N | Disease duration ≤24 months | N | Disease duration ≤36 months | N | Disease duration ≤60 months | |
|---|---|---|---|---|---|---|
| All subjects without mRSS cut point | 123 | 13 (10.57%) | 179 | 19 (10.61%) | 235 | 25 (10.64%) |
| Proportion who worsen with mRSS ≤26 (worsen/total cohort with mRSS ≤26) | 79 | 15.19% | 119 | 15.13% | 155 | 15.48% |
| Probability of worsening for mRSS ≤26 (worsen with mRSS≤26/all patients who worsened) | 13 | 92.31% | 19 | 94.74% | 25 | 96.0% |
| Probability of improvement with mRSS ≤26 (improved*/total cohort with mRSS ≤26) | 29 | 38.66% | 46 | 38.66% | 60 | 38.71% |
*Defined as mRSS improvement of >5 units and ≥25%.