Disease activity measuresr
hsCRP0.60**
DAS28-CRP0.43**
ESR0.32**
DAS28-ESR0.27**
SDAI0.27**
HAQ-DI0.24**
Patient's Global Assessment of Arthritis Pain0.23**
Physician's Global Assessment of Disease Activity0.23**
American College of Rheumatology Change from Baseline (ACR-N)−0.20*
Patient's Global Assessment of Disease Activity0.18*
TJC (68 joints)0.17*
CDAI0.16*
SJC (66 joints)0.04
  • Pearson partial correlation coefficient (r) assessed relationship between MBDA score and absolute changes from baseline at Wk 12 in the combined dose group. **p≤0.001, *p<0.05. P-value calculation based on Pearson correlation inference test. ACR-N measures % improvement from baseline.