Table 2

Modified Stoke Ankylosing Spondylitis Spine Score at baseline and end of year 2; baseline-adjusted mean changes for patients with complete sets of radiographs and patients of the intention-to-treat (ITT) population

 Patients with complete sets of radiographsITT population
nBaselineYear 2Mean change from baseline (95% CI) adjusted for baseline statusMean change from baseline (95% CI) adjusted for baseline status
Continuous treatment6210.9 (15.5)12.2 (16.7)1.28 (0.7 to 1.9)1.29 (0.7 to 1.9)
On-demand treatment6016.4 (18.2)17.2 (18.6)0.79 (0.2 to 1.4)0.71 (0.1 to 1.3)
p Value for differences between both groups0.100.130.390.16
Only patients with syndesmophytes at baseline
 Continuous treatment3319.4 (17.2)21.5 (18.2)2.11 (1.1 to 3.1)2.10 (1.1 to 3.1)
 On-demand treatment3725.9 (17.4)26.8 (17.8)0.95 (0.0 to 1.9)0.89 (0.0 to 1.8)
 p Value for differences between both groups0.080.160.100.07
Only patients with CRP >5 mg/L at baseline
 Continuous treatment3413.9 (17.9)15.6 (19.6)1.68 (0.7 to 2.6)1.67 (0.7 to 2.6)
 On-demand treatment3519.3 (19.0)20.3 (19.3)0.96 (0.0 to 1.9)0.84 (0.1 to 1.7)
 p Value for differences between both groups0.200.220.280.20
  • CRP, C reactive protein.