Table 1

Basic characteristics of the study population

 GO-BEFORE Study
All SubjectsMRI Sub-Study
N637291
Age (years)49.5 (12.3)49.0 (12.6)
Female, N (%)528 (82.9)237 (81.4)
Race
 Asian, N (%)117 (18.4)75 (25.8)
 White, N (%)461 (72.4)190 (65.3)
Disease duration (years)1.2 (0.5, 4)1.2 (0.6, 3.3)
DAS28(CRP)5.72 (1.06)5.60 (1.06)
CRP (mg/dL)1.3 (0.5, 3.4)1.2 (0.5, 2.7)
HAQ, baseline1.53 (0.67)1.56 (0.69)
HAQ, 104 weeks0.76 (0.72)0.76 (0.75)
CCP positive, N (%)468 (73.5)222 (76.3)
vdHS, baseline6 (2, 21)5.5 (2, 21.5)
RAMRIS scores
 Synovitis, baseline9.5 (5.0)
 Bone oedema, baseline10.0 (10.0)
 Bone erosion, baseline14.5 (10, 22.5)
  • CCP, cyclic citrullinated peptide antibody; CRP, C reactive protein; DAS28, disease activity score of 28 joints; HAQ, heath assessment questionnaire; RAMRIS, rheumatoid arthritis MRI score; RCT, randomized clinical trial; TNF, tumour necrosis factor; vdHS, van der Heijde-Sharp.