Table 3

Association between all autoantibodies and HAQ and DAS28

Univariate
β (95% CI)
Multivariate†
β (95% CI)
HAQ
 ACPA0.20 (0.12 to 0.28)**0.12 (0.02 to 0.21)*
 RF0.12 (0.05 to 0.18)**−0.03 (−0.12 to 0.05)
 Anti-CarP antibodies0.21 (0.14 to 0.29)**0.13 (0.03 to 0.21)*
DAS28
 ACPA0.36 (0.23 to 0.50)**0.26 (0.09 to 0.43)**
 RF0.28 (0.17 to 0.39)**−0.01 (−0.17 to 0.15)
 Anti-CarP antibodies0.38 (0.26 to 0.50)**0.25 (0.09 to 0.42)**
  • *p<0.05.

  • **p<0.01.

  • †Adjusted for age, gender, smoking status, polynomials of disease duration and year of recruitment.

  • ACPA, anticitrullinated protein antibodies; anti-CarP, anticarbamylated protein; DAS28, 28 joint disease activity score; HAQ, Health Assessment Questionnaire; RF, rheumatoid factor.