Conditional analysis of SNP associations at RUNX3
| Chr. | SNP | Position* | Risk/non-risk allele | Conditional SNP | p Value | OR | RAF (case–control) | LD (r2/D′) with conditional SNP |
|---|---|---|---|---|---|---|---|---|
| 1 | rs6600247 | 25177701 | C/T | rs4648889 | 0.9 | 1.01 | 0.54/0.51 | 0.90/0.97 |
| rs4265380 | 1.5×10−4 | 1.64 | 0.97/1 | |||||
| rs7529070 | 4.9×10−5 | 1.67 | 0.97/1 | |||||
| 1 | rs4648889 | 25166416 | A/G | rs6600247 | 0.2 | 0.84 | 0.54/0.50 | 0.90/0.97 |
| rs4265380 | 2.1×10−6 | 3.96 | 0.94/1 | |||||
| rs7529070 | 3.0×10−6 | 2.87 | 0.94/1 | |||||
| 1 | rs4265380 | 25165943 | T/C | rs6600247 | 1.0×10−6 | 0.53 | 0.55/0.50 | 0.97/1 |
| rs4648889 | 1.7×10−7 | 0.22 | 0.94/1 | |||||
| rs7529070 | 0.6 | 1.14 | 1/1 | |||||
| 1 | rs7529070 | 25168167 | A/G | rs6600247 | 2.1×10−7 | 0.52 | 0.53/0.50 | 0.97/1 |
| rs4648889 | 1.2×10−7 | 0.30 | 0.94/1 | |||||
| rs4265380 | 0.3 | 0.77 | 1/1 |
*National Center for Biotechnology Information (NCBI) Build 36 human genome coordinates.
Chr., chromosome; LD, linkage disequilibrium; RAF, risk allele frequency; SNP, single nucleotide polymorphism.