Baseline | 2 months | Change (2 months–baseline) | p Value* | 6 months | Change (6 months-–baseline) | p Value† | |
---|---|---|---|---|---|---|---|
Mean circumference of F1–F5 (ring size) | |||||||
Dominant hand | |||||||
Mean±SD | 61.9±2.2 | 60.7±2.3 | −1.2±1.4 | 0.013 | 59.8±2.4 | −2.1±1.1 | <0.001 |
Median (range) | 61.8 (58.8–66) | 60.8 (57–65) | −0.9 (−4.6–0.6) | 60 (56–64.4) | −2.3 (−4.6–−0.4) | ||
Non-dominant hand | |||||||
Mean±SD | 60.7±2.3 | 59.3±1.7 | −1.3±1.4 | 0.008 | 58.1±2.2 | −2.5±1.5 | <0.001 |
Median (range) | 61 (57–64.2) | 59 (56.8–63.4) | −1.2 (−3.4–0.8) | 58 (54–62.8) | −2.5 (−4.8–0.4) | ||
MRSS applied to hand/18 | |||||||
Whole population | |||||||
Mean±SD | 10.9±4.9 | 10.0±5.3 | −0.9±1.6 | 0.067 | 9.9±6.0 | −1.0±2.8 | 0.246 |
Median (range) | 11.5 (3–18) | 10.5 (2–18) | −0.5 (−4–1) | 12 (1–18) | −2 (−5–4) | ||
Global MRSS/51 | |||||||
Whole population | |||||||
Mean±SD | 13.9±9.8 | 11.7±9.8 | −2.3±2.5 | 0.010 | 11.5±10.1 | −2.4±2.8 | 0.013 |
Median (range) | 12 (3–32) | 9 (2–29) | −2 (−6–3) | 8.5 (1–29) | −2 (−7–2) |
Bold values correspond to the p value columns. p≤0.05 (2-sided) was considered significant.
Data are mean±SD.
*p Value from baseline to M2.
†p Value from baseline to M6.
Data are mean±SD.
F1–F5, finger 1–finger 5; MRSS, Modified Rodnan skin score.