Table 1

Calculation of the RABBIT Risk Score

Risk factorsV.1: Number of serious infections per 100 PYsV.2: Percentage of patients with at least one infection per year
InterceptAlways add−3.996−4.191
AgeIf age >60 add0.4790.470
Function (FFbH)Add−0.01014*FFbH−0.00865*FFbH
Alternatively: HAQAdd0.362(HAQ-3.16)0.309(HAQ-3.16)
Chronic lung diseaseIf yes add0.5220.484
Chronic renal diseaseIf yes add0.4410.415
Previous serious infectionIf yes add0.7480.992
Number of treatment failuresIf >5 add0.4430.397
Mean glucocorticoid doseIf 7.5–14 mg/day add0.7560.782
Mean glucocorticoid doseIf ≥ 15 mg/day add1.5541.355
Treatment with TNF inhibitorIf yes (last 3 months) add0.5930.589
Calculate the sum of the corresponding valuesSum1Sum2
Rabbit Risk ScoreCalculateEmbedded ImageEmbedded Image
  • FFbH, Hannover Functional Status Questionnaire, Funktionsfragebogen Hannover; HAQ, Health Assessment Questionnaire; PY, patient-years; RABBIT, Rheumatoid Arthritis Observation of Biologic Therapy; TNF, tumour necrosis factor.