Characteristics of the study samples
| FHS | GARP | RS1 | RS3 | TUK | |
|---|---|---|---|---|---|
| N | 330 | 192 | 2440 | 974 | 744 |
| Age (years) | 54.3 (11.0) | 60.3 (7.1) | 65.7 (6.7) | 54.7 (3.4) | 53.6 (8.3) |
| Women (%) | 42.2 | 79.7 | 57 | 59 | 96.8 |
| BMI (kg/m2) | 28.1 (5.1) | 26.44 (4.8) | 26.3 (3.4) | 27.12 (4.6) | 24.9 (4.4) |
| Lumbar spine imaging | CT | Radiograph | Radiograph | Radiograph | MRI |
| LDD variable | 2.49 (0.97) | 0.02 (0.958) | 0.006 (0.978) | 0.011 (0.965) | 3.46 (1.14) |
Values are mean (SD) unless specified otherwise.
BMI, body mass index; FHS, Framingham Heart Study; GARP, Genetics of OsteoArthrosis and Progression study; LDD, Lumbar disc degeneration; RS1, Rotterdam study cohort 1; RS3, Rotterdam study cohort 3; TUK, TwinsUK.