COMPASS score | |||
---|---|---|---|
COMPASS domain | PSS | Controls | PSS vs controls* |
Orthostatic intolerance | 12.5 (2.5–17.5) | 0.0 (0.0–12.5) | <0.0001 |
Vasomotor | 0.0 (0.0–5.0) | 0.0 (0.0–0.0) | <0.0001 |
Secretomotor | 7.5 (7.5–9.0) | 1.5 (0.0–4.5) | <0.0001 |
Gastroparesis | 0.0 (0.0–1.7) | 0.0 (0.0–0.0) | 0.0001 |
Autonomic diarrhoea | 0.0 (0.0–8.0) | 2.0 (0.0–8.0) | 0.21 |
Constipation | 1.5 (0.0–3.0) | 1.5 (0.0–3.0) | 0.25 |
Bladder control | 2.0 (0.0–4.0) | 2.0 (0.0–2.0) | 0.0002 |
Pupil and focusing | 2.0 (1.0–3.0) | 0.5 (0.0–1.5) | <0.0001 |
Sleep disorders | 1.5 (0.0–2.3) | 0.0 (0.0–1.5) | <0.0001 |
Syncope | 0.0 (0.0–0.0) | 0.0 (0.0–0.0) | 0.35 |
COMPASS total | 35.5 (20.9–46.0) | 14.8 (4.4–30.2) | <0.0001 |
Understatement | 1.7 (0.0–3.3) | 6.0 (2.0–8.0) | <0.0001 |
Overstatement | 0.0 (0.0–1.8) | 0.0 (0.0–7.0) | <0.0001 |
Values are median (IQR).
↵* Wilcoxon matched pairs test.
COMPASS, Composite Autonomic Symptom Scale; PSS, primary Sjögren's syndrome.