Periarticular bone changes in the psoriasis patients and healthy controls
| Psoriasis patients | Healthy controls | p Value* | |||
|---|---|---|---|---|---|
| Number of subjects | 55 | 47 | |||
| Erosions total, N | 27 | 18 | |||
| Erosions/patient, N | 0.5 | 0.4 | |||
| Erosions, mean±SD | 0.49±0.94 | 0.39±0.65 | 0.99 | ||
| Metacarpal head 2 N (%) | 15 (55) | 9 (50) | |||
| Phalangeal base 2 N (%) | 1 (4) | 1 (6) | |||
| Metacarpal head 3 N (%) | 10 (37) | 8 (44) | |||
| Phalangeal base 3 N (%) | 1 (4) | 0 (0) | |||
| Enthesiophytes total, N | 306 | 138 | |||
| Enthesiophytes/patient, N | 6 | 3 | |||
| Enthesiophytes, mean±SD | 5.62±3.30 | 3.04±1.81 | <0.001 | ||
| Metacarpal head 2, N (%) | 113 (37) | 55 (40) | |||
| Phalangeal base 2, N (%) | 64 (21) | 32 (24) | |||
| Metacarpal head 3, N (%) | 71 (23) | 33 (23) | |||
| Phalangeal base 3, N (%) | 58 (19) | 18 (13) | |||
| Mean±SD | Min–Max | Mean±SD | Min–Max | ||
| Total volume (Erosions)† | |||||
| Metacarpal head 2 (mm3) | 1.95±0.94 | 0.25–6.10 | 2.54±3.77 | 0.23–11.97 | 0.76 |
| Phalangeal base 2 (mm3) | 5.2 | 5.2 | 0.27 | 0.27 | –‡ |
| Metacarpal head 3 (mm3) | 3.21±2.37 | 0.26–7.45 | 2.87±2.31 | 0.33–6.66 | 0.88 |
| Phalangeal base 3 (mm3) | 0.28 | 0.28 | – | – | – |
| Total height (enthesiophytes)† | |||||
| Metacarpal head 2 (mm) | 1.68±0.78 | 0.54–3.69 | 1.20±0.47 | 0.45–2.04 | <0.001 |
| Phalangeal base 2 (mm) | 1.27±0.72 | 0.43–3.14 | 0.73±0.27 | 0.30–1.42 | 0.001 |
| Metacarpal head 3 (mm) | 1.19±0.56 | 0.40–3.30 | 0.78±0.34 | 0.44–1.72 | 0.005 |
| Phalangeal base 3 (mm) | 1.18±0.71 | 0.39–3.88 | 0.76±0.20 | 0.40–1.04 | <0.001 |
*p Values are presented for interval data.
†Volume (target erosion) and height (target enthesiophyte) are expressed as the sum of the measures obtained in each quadrant for each examined compartment.
‡Values are not a mean but correspond to measure of a single counted erosion (see panel up) in each group; no inferential comparison has been made.