Percentages of good long-term renal responders according to type of response at 3 months, 6 months and 12 months, defined using different criteria sets*
| Criteria to define response | 3 months | 6 months | 12 months | ||||||
|---|---|---|---|---|---|---|---|---|---|
| CR | PR | NR | CR | PR | NR | CR | PR | NR | |
| Proteinuria | 89 (24/27) | 92 (24/26) | 70 (28/40) | 90 (38/42) | 75 (18/24) | 67 (18/27) | 92 (47/51) | 86 (19/22) | 47 (9/19) |
| Proteinuria +sCr | 91 (21/23) | 92 (23/25) | 70 (33/47) | 92 (36/39) | 80 (16/20) | 63 (22/35) | 94 (44/47) | 90 (19/21) | 46 (12/26) |
| Proteinuria + sCr + uRBCs | 100 (9/9) | 89 (31/35) | 70 (33/47) | 100 (13/13) | 85 (34/40) | 63 (22/35) | 93 (28/30) | 91 (30/33) | 46 (12/26) |
*Figures are percentages (and values in brackets are numbers) of good long-term renal responders within patients achieving CR, PR and NR, at different time sets. According to timing and criteria sets, not all 105 patients could be evaluated for CR, PR or NR, due to missing lab data. Good long-term renal outcome was defined as a last serum creatinine value ≤120% of baseline. For definitions of CR, PR and NR, see table 3.
CR, complete response; NR, no response; PR, partial response; sCr, serum creatinine; uRBCs, urinary red blood cells.