Logistic regression model to assess association between the variables included in the final classification criteria and the experts’ consensus of patients’ classification as having or not having macrophage activation syndrome*
| Explanatory variable | OR (95% CI) | p Value† |
|---|---|---|
| Ferritin >684 ng/mL | >999.999 (40.6 to >999.999) | <0.0001 |
| Platelet count ≤181×109/L | 237.0 (18.2 to >999.999) | <0.0001 |
| Triglycerides >156 mg/dL | 18.3 (2.0 to 163.9) | 0.009 |
| Fibrinogen ≤360 mg/dL | 16.0 (2.0 to 126.4) | 0.009 |
| Aspartate aminotransferase >48 units/L | 10.0 (1.3 to 78.4) | 0.029 |
*The experts’ consensus on patients’ classification as having or not having macrophage activation syndrome (from the web-based process) was the dependent variable. Complete data were available on 227 patients. The area under the receiver operating characteristic curve of the model was 0.99.
†By likelihood ratio test.