Table 2

Conditional logistic regression analysis for occurrence of effusion-synovitis and Hoffa-synovitis in the study population including the model adjusted for injury/surgery at baseline

TotalCases
N (%)
Controls
N (%)
ORs* (95% CI)Adjusted OR† (95% CI)
Baseline effusion-synovitis
 Present9050 (37.59)40 (30.08)1.56 (0.86 to 2.81)1.41 (0.77 to 2.58)
P-1 effusion-synovitis
 Present10366 (52.80)37 (29.60)3.23 (1.72 to 6.06)2.63 (1.35 to 5.13)
P0 effusion-synovitis
 Present12782 (65.60)45 (36.00)4.70 (2.35 to 9.40)5.00 (2.42 to 10.35)
Baseline Hoffa-synovitis
 Present10261 (46.21)41 (30.83)1.80 (1.10 to 2.95)2.06 (1.21 to 3.50)
P-1 Hoffa-synovitis
 Present10466 (53.23)38 (30.40)2.47 (1.45 to 4.23)3.05 (1.72 to 5.44)
P0 Hoffa-synovitis
 Present11069 (55.65)41 (33.06)2.40 (1.43 to 4.04)2.66 (1.57 to 4.51)
  • *GEE method with a robust sandwich estimator was used to account for the correlation of two knees within an individual.

  • †Adjusted for self-reported knee injury, knee surgery at baseline, BMI and knee bending activities.

  • BMI, body mass index; GEE, general estimated equations; P1, 1 year prior to occurrence of ROA; P0, point of occurrence of ROA; ROA, radiographic knee osteoarthritis.