Characteristics of the fracture risk prediction tools
| Characteristics | |||||
|---|---|---|---|---|---|
| Tool | Number of clinical risk factors* | BMD | Tool accessibility Gender Age range | Prediction time(s) and outcome(s) | Number of studies |
| ‘Computer model for osteoporotic fracture risk’ | 8 | Yes | Request from authors Female only 45–79 | 5 years Absolute fracture risk Expected absolute risk reduction after treatment | 135 |
| FRAMO | 4 | No | Available in article Male/Female 70–100 | 2 years Hip fracture risk Mortality | 236 37 |
| FRAX | 11 | Optional | http://www.shef.ac.uk/FRAX Male/Female 40–90 | 10 years Major osteoporotic fracture risk Hip fracture risk | 2632 38–62 |
| FRC | 12† | Yes | https://riskcalculator.fore.org/ Male/Female ≥45 | 10 years Hip fracture risk | 263 64 |
| FRISC | 8 | Yes | http://www.biostatistics.jp/prediction/frisc Female only 40–100 | 1, 3, 5 and 10 years Major osteoporotic fracture risk Immobilisation risk | 259 65 |
| FRISK | 5 | Yes | Available in article Male/Female >60 | 5 and 10 years Major osteoporotic fracture risk | 266 67 |
| GARVAN-GRX | 5 | Optional | http://garvan.org.au/promotions/bone-fracture-risk/calculator/ Male/Female 60–96 | 5 and 10 years Any osteoporotic/fragility fracture risk Hip fracture risk | 634 39 54 55 68 69 |
| QFracture | 19 | No | Removed from website in 2012 Male/Female 30–85 | 1–10 years Any osteoporotic fracture risk Hip fracture risk | 333 42 70 |
| Updated QFracture (2012) | 31 | No | http://www.qfracture.org/ Male/Female 30–99 | 1–10 years Any osteoporotic fracture risk Hip fracture risk | 171 |
| Score for estimating the long-term risk of fracture in post-menopausal women | 8 | No | Available in article Females only ≥50 | 5 years Clinical vertebral fracture risk Clinical osteoporotic fracture risk Hip fracture risk | 172 |
| Simplified fracture risk system | 5 | Yes | Available in article Female only ≥50 | 10 years Any fracture risk | 173 |
| SOF | 14 | No | Available in article Female only Age unclear | 5 years Hip fracture risk | 174 |
| WHI | 11 | No | Request from authors Females only ≥50 | 5 years Hip fracture risk | 175 |
*Bone mineral density (BMD) was not considered.
Additional descriptions are provide in online supplementary table S3.
†An updated version of the website, dated September 2014, also includes BMD of spine, glucocorticoid exposure, and previous spine fracture, which were not part of the original publication included in this SR. No further publications supporting this change could be found.
FRISC, Fracture and Immobilization Score; FRISK, Fracture Risk prediction; SR, systematic review.